大鼠混合肝微粒体,来源于雄性Sprague-Dawley大鼠,20mg/ml,0.5ml These microsomes are prepared from a pool of male Sprague-Dawley rats.• Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• testosterone 6(beta)-hydroxylase
• testosterone 16(alpha)-hydroxylase
• lauric acid 12-hydroxylase
• cytochrome c reductase
大鼠混合S9,雄性供者来源,20mg/ml,1ml These tissue fractions are prepared from a pool of male Sprague-Dawley rats. • Available size: 1.0 ml. • Total protein concentration: 20 mg/ml
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-hydroxycoumarin sulfotransferase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
狗肝微粒体,来源于雄性Beagle,20mg/ml,0.5ml These microsomes are prepared from a pool of male beagle dogs.
• Available size: 0.5 ml.
• Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
• Lauric acid 12-hydroxylase, and cytochrome c reductase
小鼠混合S9,来源于雄性CD-1小鼠,20mg/ml,1ml These tissue fractions are prepared from a pool of male or female CD-1 mice.
• Total protein concentration: 20mg/mL
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-hydroxycoumarin sulfotransferase
• Testosterone 6(beta)-hydroxylase
人组织片段匀浆后可溶性蛋白溶质混合液,150人份混合性别供者,20mg/ml,1ml。1,保证了批内批间最小误差,使实验结果准确、重复性高,2,出厂时经过严格检验,安全可靠。3,含有NAT, GST, SULT成分。 The pooled mixture enables consistency in experimental results in multi-site and long-term programs by delivering reproducible data across multiple CYP and UGT enzymes as compared to smaller pools of donors.
Features
• Provides lot-to-lot consistency based on activity of the major CYPs (CYP 1A2, 2C9, 2C19, 2D6, 3A4); suitable for metabolic stability, CYP inhibition and reaction phenotyping assays
• Enables availability of large lots for multi-year and multi-site programs
• Saves researcher time with extensive characterization of CYP, UGT, and FMO enzyme activity, and Western Blots
• Supports strict tissue traceability and sourcing from US-based Organ Procurement Organizations meeting high ethical standards.
• Adheres to high safety standards including serological testing prior to acceptance, followed by PCR testing for HIV I/II, Hepatitis B, Hepatitis C, HTLV 1/2 (human Tcell leukemia virus) pathogens, and CMV (cytomegalovirus)
小鼠肝微粒体,来源于雄性CD-1小鼠,20mg/ml,0.5ml These microsomes are prepared from a pool of male or female CD-1 mice.
• Available size: 0.5 ml.
• Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• Testosterone 6(beta)-hydroxylase
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Lauric acid 12-hydroxylase
• Cytochrome c reductase
人肝微粒体混合液S9片段,来源于不同性别的人类供体,含有多种CYP酶,20mg/ml,1ml。 This product is a pooled mixture of liver S9 from different individual donors. Pathogenicity testing of each liver was performed, and each was found to be negative for HIV1&2, HTLV1&2, and hepatitis B&C. Available size: 1 mL.
• Total protein concentration: 20 mg/mL.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on each product insert:
• phenacetin O-deethylase
• coumarin 7-hydroxylase
• (S)-mephenytoin N-demethylase
• paclitaxel 6(alpha)-hydroxylase
• diclofenac 4'-hydroxylase
• (S)-mephenytoin 4'-hydroxylase
• bufuralol 1'-hydroxylase
• chlorzoxazone 6-hydroxylase
• testosterone 6(beta)-hydroxylase
兔肝微粒体,供者为雄性新西兰小白兔,20mg/ml,0.5ml These microsomes are prepared from a pool of male New Zealand white rabbits. • Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
• Lauric acid 12-hydroxylase, and cytochrome c reductase
大鼠混合细胞溶质,雄性供者来源,20mg/ml,1ml This cytosol is prepared from a pool of male Sprague-Dawley rats.• Available size: 1.0 ml.• Total protein concentration: 20 mg/ml
• Catalytic activities (pmol/(mg x min) for the following assay is provided on the product insert:
• 7-hydroxycoumarin sulfotransferase
Shipping:dry-ice
Preparation and Storage: -80
狗肝微粒体混合液S9片段,来源于雄性Beagle,20mg/ml,1ml These tissue fractions are prepared from a pool of male beagle dogs.
• Available size: 1.0 ml.
• Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-hydroxycoumarin sulfotransferase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
大鼠混合肝微粒体,来源于雌性Sprague-Dawley大鼠,20mg/ml,0.5ml These microsomes are prepared from a pool of female Sprague-Dawley rats.• Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Lauric acid 12-hydroxylase
• Cytochrome c reductase