大鼠混合肝微粒体，来源于雄性Sprague-Dawley大鼠，20mg/ml，0.5ml These microsomes are prepared from a pool of male Sprague-Dawley rats.• Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• testosterone 6(beta)-hydroxylase
• testosterone 16(alpha)-hydroxylase
• lauric acid 12-hydroxylase
• cytochrome c reductase
大鼠混合S9，雄性供者来源，20mg/ml，1ml These tissue fractions are prepared from a pool of male Sprague-Dawley rats. • Available size: 1.0 ml. • Total protein concentration: 20 mg/ml
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-hydroxycoumarin sulfotransferase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
狗肝微粒体，来源于雄性Beagle，20mg/ml，0.5ml These microsomes are prepared from a pool of male beagle dogs.
• Available size: 0.5 ml.
• Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
• Lauric acid 12-hydroxylase, and cytochrome c reductase
小鼠混合S9，来源于雄性CD-1小鼠，20mg/ml，1ml These tissue fractions are prepared from a pool of male or female CD-1 mice.
• Total protein concentration: 20mg/mL
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-hydroxycoumarin sulfotransferase
• Testosterone 6(beta)-hydroxylase
人组织片段匀浆后可溶性蛋白溶质混合液，150人份混合性别供者，20mg/ml，1ml。1，保证了批内批间最小误差，使实验结果准确、重复性高,2，出厂时经过严格检验，安全可靠。3，含有NAT, GST, SULT成分。 The pooled mixture enables consistency in experimental results in multi-site and long-term programs by delivering reproducible data across multiple CYP and UGT enzymes as compared to smaller pools of donors.
Features
• Provides lot-to-lot consistency based on activity of the major CYPs (CYP 1A2, 2C9, 2C19, 2D6, 3A4); suitable for metabolic stability, CYP inhibition and reaction phenotyping assays
• Enables availability of large lots for multi-year and multi-site programs
• Saves researcher time with extensive characterization of CYP, UGT, and FMO enzyme activity, and Western Blots
• Supports strict tissue traceability and sourcing from US-based Organ Procurement Organizations meeting high ethical standards.
• Adheres to high safety standards including serological testing prior to acceptance, followed by PCR testing for HIV I/II, Hepatitis B, Hepatitis C, HTLV 1/2 (human Tcell leukemia virus) pathogens, and CMV (cytomegalovirus)
小鼠肝微粒体，来源于雄性CD-1小鼠，20mg/ml，0.5ml These microsomes are prepared from a pool of male or female CD-1 mice.
• Available size: 0.5 ml.
• Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• Testosterone 6(beta)-hydroxylase
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Lauric acid 12-hydroxylase
• Cytochrome c reductase
人肝微粒体混合液S9片段，来源于不同性别的人类供体，含有多种CYP酶，20mg/ml，1ml。 This product is a pooled mixture of liver S9 from different individual donors. Pathogenicity testing of each liver was performed, and each was found to be negative for HIV1&2, HTLV1&2, and hepatitis B&C. Available size: 1 mL.
• Total protein concentration: 20 mg/mL.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on each product insert:
• phenacetin O-deethylase
• coumarin 7-hydroxylase
• (S)-mephenytoin N-demethylase
• paclitaxel 6(alpha)-hydroxylase
• diclofenac 4'-hydroxylase
• (S)-mephenytoin 4'-hydroxylase
• bufuralol 1'-hydroxylase
• chlorzoxazone 6-hydroxylase
• testosterone 6(beta)-hydroxylase
兔肝微粒体，供者为雄性新西兰小白兔，20mg/ml，0.5ml These microsomes are prepared from a pool of male New Zealand white rabbits. • Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
• Lauric acid 12-hydroxylase, and cytochrome c reductase
大鼠混合细胞溶质，雄性供者来源，20mg/ml，1ml This cytosol is prepared from a pool of male Sprague-Dawley rats.• Available size: 1.0 ml.• Total protein concentration: 20 mg/ml
• Catalytic activities (pmol/(mg x min) for the following assay is provided on the product insert:
• 7-hydroxycoumarin sulfotransferase
Shipping:dry-ice
Preparation and Storage: -80
狗肝微粒体混合液S9片段，来源于雄性Beagle，20mg/ml，1ml These tissue fractions are prepared from a pool of male beagle dogs.
• Available size: 1.0 ml.
• Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-hydroxycoumarin sulfotransferase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
大鼠混合肝微粒体，来源于雌性Sprague-Dawley大鼠，20mg/ml，0.5ml These microsomes are prepared from a pool of female Sprague-Dawley rats.• Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Lauric acid 12-hydroxylase
• Cytochrome c reductase
大鼠混合肝微粒体，来源于雄性Wistar Han大鼠，20mg/ml，0.5ml These microsomes are prepared from a pool of male Wistar Han rats.• Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• testosterone 6(beta)-hydroxylase
• testosterone 16(alpha)-hydroxylase
• lauric acid 12-hydroxylase
• Cytochrome c reductase
Shipping:dry-ice
Preparation and Storage: -80
人肝微粒体HLM，来源于20位不同性别的人类供体，20mg/ml，0.5ml。 This is a pooled mixture of liver microsomes from different individual donors. Pathogenicity testing of each liver was performed, and each was found to be negative for HIV1&2, HTLV1&2, and hepatitis B&C.
小鼠肝微粒体，来源于雄性B6C3F1小鼠，20mg/ml，0.5ml。 These microsomes are prepared from a pool of male B6C3F1 mice.• Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• Testosterone 6(beta)-hydroxyl
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Lauric acid 12-hydroxylase
• Cytochrome c reductas
人肝微粒体混合液S9片段，来源于150位不同性别的人类供体，含有多种CYP酶，20mg/ml，1ml。1，保证了批内批间最小误差，使实验结果准确、重复性高,2，出厂时经过严格检验，安全可靠。3，适合于CYP代谢、CYP酶引起的表观遗传学研究等。 The pooled mixture enables consistency in experimental results in multi-site and long-term programs by delivering reproducible data across multiple CYP and UGT enzymes as compared to smaller pools of donors.
Features
• Provides lot-to-lot consistency based on activity of the major CYPs (CYP 1A2, 2C9, 2C19, 2D6, 3A4); suitable for metabolic stability, CYP inhibition and reaction phenotyping assays
• Enables availability of large lots for multi-year and multi-site programs
• Saves researcher time with extensive characterization of CYP, UGT, and FMO enzyme activity, and Western Blots
• Supports strict tissue traceability and sourcing from US-based Organ Procurement Organizations meeting high ethical standards.
• Adheres to high safety standards including serological testing prior to acceptance, followed by PCR testing for HIV I/II, Hepatitis B, Hepatitis C, HTLV 1/2 (human Tcell leukemia virus) pathogens, and CMV (cytomegalovirus) Specification
Product Characterization
Assay: Enzymes
CYP: CYP1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, 3A, 4A11
Western Blot: CYP 3A4, 3A5
UGT: UGT1A1, 1A4, 1A6, 1A9, 2B7
Others: FMO, Total Cytochrome P450 content, Cytochrome P450 oxidoreductase, Cytochrome b5 content
猴肝微粒体，来源于雄性猿猴，20mg/ml，0.5ml。 These microsomes are prepared from a pool of male or female cynomolgus monkeys.• Available size: 0.5 ml • Total protein concentration: 20 mg/ml
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• testosterone 6(beta)-hydroxylase
• p-nitrophenol hydroxylase
• Lauric acid 12-hydroxylase
人肝微粒体，供者全部为男性，20mg/ml，0.5ml These pools are formulated from materials derived from five or more male donors. Single gender pools can be used to examine for gender-related differences in metabolism. Pathogenicity testing of each liver was performed, and each was found to be negative for HIV1&2, HTLV1&2, and hepatitis B&C
小鼠肝微粒体，来源于雌性CD-1小鼠，20mg/ml，0.5ml 20mg/mL protein concentration
• Available size: 0.5 ml.
• Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• Testosterone 6(beta)-hydroxylase
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Lauric acid 12-hydroxylase
• Cytochrome c reductase
人肝微粒体HLM，来源于150位不同性别的人类供体，含有多种CYP酶，20mg/ml，0.5ml。1，保证了批内批间最小误差，使实验结果准确、重复性高,2，出厂时经过严格检验，安全可靠。3，适合于CYP代谢、CYP酶引起的表观遗传学研究等。 The pooled mixture of liver microsomes enables consistency in experimental results in multi-site and long-term programs by delivering reproducible data across multiple CYP and UGT enzymes as compared to smaller pools of donors.
Features
• Provides lot-to-lot consistency based on activity of the major CYPs (CYP 1A2, 2C9, 2C19, 2D6, 3A4); suitable for metabolic stability, CYP inhibition and reaction phenotyping assays
• Enables availability of large lots for multi-year and multi-site programs
• Saves researcher time with extensive characterization of CYP, UGT, and FMO enzyme activity, and Western Blots
• Supports strict tissue traceability and sourcing from US-based Organ Procurement Organizations meeting high ethical standards.
• Adheres to high safety standards including serological testing prior to acceptance, followed by PCR testing for HIV I/II, Hepatitis B, Hepatitis C, HTLV 1/2 (human Tcell leukemia virus) pathogens, and CMV (cytomegalovirus)
狗肝微粒体，来源于雌性Beagle，20mg/ml，0.5ml These microsomes are prepared from a pool of female beagle dogs.
• Available size: 0.5 ml.
• Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Testosterone 6(beta)-hydroxylase
• Testosterone 16(alpha)-hydroxylase
• Lauric acid 12-hydroxylase
• Cytochrome c reductase
迷你猪肝微粒体，来源于雄性Gottingen迷你猪，20mg/ml，0.5ml These microsomes are prepared from a pool of male Gottingen mini-pigs.• Available size: 0.5 ml. • Total protein concentration: 20 mg/ml.
• Catalytic activities (pmol/(mg x min) for the following assays are provided on the product insert:
• Testosterone 6(beta)-hydroxyl
• 7-ethoxyresorufin O-deethylase
• p-nitrophenol hydroxylase
• Lauric acid 12-hydroxylase
• Cytochrome c reductas
人肝微粒体，供者全部为女性，20mg/ml，0.5ml These pooled mixtures are formulated from materials derived from five or more female donors. Single gender pools can be used to examine for gender-related differences in metabolism. Pathogenicity testing of each liver was performed, and each was found to be negative for HIV1&2, HTLV1&2, and hepatitis B&C.
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